More articles about: Medication Interactions
cells in green and purple and black background under microscope
Health Lab
Tiny model organs detect liver toxicity of new drugs
A University of Michigan-led study provided evidence of the efficacy of a new drug-induced liver injury screening platform using human liver organoids, or tiny 3D models of organs developed from patients’ stem cells that grow in petri dishes.
older woman at table with medicine pills in front of her
Health Lab
"Deprescribing" medicines for older adults: Patient-provider dialogue needed
Stopping or reducing doses of prescription medicine, also called deprescribing, is something many older adults would like to do, and some have already done without medical guidance. Medication reviews could help.
patient ICU hospital machine vitals
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Anti-anaerobic antibiotics associated with increased risk of mortality in critically ill patients
Study shows early treatment with specific antibiotics depletes the body of gut anaerobes that protect against pneumonia, organ failure and mortality.
Man with glasses sitting on edge of furniture leaning, holding his shoulder.
Health Lab
Aching joints make older adults reach for many forms of pain relief – but health risks could follow
Arthritis – both osteoarthritis and rheumatoid arthritis – affects most adults over 50 and limits the activity of many. Pain drugs and supplements to ease pain can interact and cause health risks.
pill stethoscope money bottle
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Cost of brand-name epilepsy drugs increased by 277% over 8 years
Generic anti-seizure drugs’ costs went down during the same time, study shows
pills
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Good news, bad news on risky medication use in nursing homes
The VA’s efforts to reduce use of risky antipsychotic medications in its nursing homes succeeded – but use of other medications with less evidence behind them rose.
Microscope lab notes
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Drugs showing promise in cancer trials reduce scarring for scleroderma
The findings could lead to repurposing drugs for patients with the sometimes-fatal condition.
pink organs bleeding from stomach in white drawing of body and teal and pink pills floating in air
Health Lab
Why are PPIs underused for the prevention of gastrointestinal bleeding?
A team examines barriers to the use of a proven strategy to protect the stomachs of patients at high risk for bleeding.
Xray image comparison of spine.
Health Lab
Drug combination reduces narcotic use, manages pain after surgery for teens with scoliosis
Narcotics after surgery often lead to side effects such as nausea, vomiting and itching.
protein pig intestine infection immune
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Drug made from pig intestine helps escape the “trap” of clot-causing immune response
Study findings bring researchers closer to the “holy grail” for neutralizing and preventing harmful blood clots that can occur in potentially several diseases.
hands scratching wrist inflammation red
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For psoriasis, molecular signature in healthy-appearing skin may be best predictor of response to anti-TNF treatment
Patients with psoriasis may hold clues in their genetic profile to predicting anti-TNF treatment response, furthering the application of precision medicine.
drawing in blue ink on lined paper of pills
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Nearly 3% of Americans Take Immune-Weakening Drugs that May Limit COVID Vaccine Response
Many are taking steroids that could increase risk of COVID-related hospitalization, researchers say.
grey outline of a brain with the left side light grey and the right side dark grey and colorful puzzle pieces floating in and out of the brain
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Troubling Trio: Many with Dementia Take Risky Combinations of Medicines
People with Alzheimer’s and other forms of dementia often receive medications for depression, anxiety, agitation, sleep problems, apathy and other behavioral issues. But combinations of three or more can be dangerous.
grey transparent lungs seeing brachial branching
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Protein Linked to Progressive Lung Scarring in Scleroderma Patients
Osteopontin is discovered as the culprit behind these patients’ main cause of death. However, a repurposed immunosuppressive drug may combat the pro-inflammatory protein.
female wearing orange tank top holding her throat in discomfort and looking down
Health Lab
Does PPI Response Predict Other Conditions?
A research scientist and his team examine the relationship between proton pump inhibitors, endoscopy, esophageal conditions and psychological distress for patients with GERD.