Researchers have made a genetic breakthrough in mice that could lead to new, revolutionary treatment options for SCN8A-related encephalopathy seizure disorder in babies.

Medical residents called interns serve as a test population to show the promise of a predictive genetics tool called a polygenic risk score in depression risk and resilience.

Gene therapy may prevent blindness from rare eye disease Leber congenital amaurosis.

The genetic disease that causes vision loss can affect all ages, including young people. Learn more about symptoms, risk factors and management.

Researchers identify genetic variants that lead to a severe developmental syndrome. The findings could mean better screening and diagnosis for patients with inherited syndromes.

A tool borrowed from bacteria successfully seeks out, cuts and destroys long stretches of human cells’ DNA, opening doors to new uses in research and treatment.

A Michigan Medicine professor and a U-M medical student created an app to help patients manage HHT, a systemic blood vessel disorder characterized by excessive nose bleeding.

Regulation of genes by noncoding DNA might help explain the complex interplay between our environment and genetic expression.

: Advances in gene therapy are yielding new options for treating inherited retinal degenerations, giving retina specialists new tools — and new hope for patients and families.

With the help of a new human embryonic stem cell line, researchers make initial strides toward treatment for the genetic mutation.

Training one gene to “pinch hit” for its twin could be a possible treatment for a type of congenital anemia, new research finds.

Read about the pros and genetic testing and some of the negatives of genetic testing, and how genetic screening tests assist in understanding disease risks.

Learn more about the most recent study from U-M’s long-standing psoriasis work, a new study that builds on the genetic architecture of psoriasis, the next step toward answering what in the genes causes the disease.

After a multigenerational diagnosis of a congenital heart defect, one close-knit Michigan family is committed to living life to the fullest.

Get answers to frequently asked questions about genetic screening for inherited heart diseases such as Marfan syndrome or hypertrophic cardiomyopathy.