More articles about: Drug Discovery
cells in green and purple and black background under microscope
Health Lab
Tiny model organs detect liver toxicity of new drugs
A University of Michigan-led study provided evidence of the efficacy of a new drug-induced liver injury screening platform using human liver organoids, or tiny 3D models of organs developed from patients’ stem cells that grow in petri dishes.
 liver in yellow blue background dT109 written across image in four spots at corners
Health Lab
Potential drug treats fatty liver disease in animal models, brings hope for first human treatment
For nonalcoholic steatohepatitis, also known as NASH, a potential drug may treat the fatty liver disease in animal models researchers find.
 pills
Health Lab
New neurology medication usage low due to high costs, similar effectiveness
Future studies are needed to determine if cost is a barrier for new medications with greater efficacy.
 lungs 3d model
Health Lab
First-of-its-kind whole lung simulator helps predict new treatments and vaccines for tuberculosis
The research team is the first to perform virtual clinical trials using a multi-scale lung model, with early results expected next year, to examine this reemerging global health threat.
 lymphoma microscopic cells image blue
Health Lab
Early study finds new lymphoma drug effective
Eighty percent of patients with a subset of lymphoma saw their cancers shrink after taking zanubrutinib in a clinical trial.
 Microscope lab notes
Health Lab
Drugs showing promise in cancer trials reduce scarring for scleroderma
The findings could lead to repurposing drugs for patients with the sometimes-fatal condition.
 stethoscope drawing in blue ink on lined paper with lab note writing on bottom right in yellow and navy
Health Lab
Clearing cholesterol crystals with a new nanoparticle
Researchers developed an HDL-mimicking nanoparticle that modified heart disease-related plaques in preclinical research.
 white brown pills on green background
Health Lab
Most Dollars Spent on Top-Selling “Orphan Drugs” Don’t Go to Treat People with Rare Diseases
Pharmaceutical companies get special protection from the FDA for orphan drugs aimed at rare diseases, but a study shows high spending for common diseases for some such drugs.
 drawing in blue ink of pills on lined paper with yellow badge on bottom right that says lab note
Health Lab
Drug Combination Prevents Clots Without Increasing Bleeding in Mouse Models
Researchers continue to hone in on how best to prevent blood clots, which cause strokes and heart attacks, without unintended side effects.
 image of drawing of gene in blue ink on lined paper with lab note written on bottom right
Health Lab
New Gene Target Could Improve Cholesterol Without Harming the Liver
Preclinical study identifies possible therapeutic target for cardiovascular risk factors that avoid the common problem of an increased risk of fatty liver disease.
 nurse getting covid vaccine saying the covid vaccine live q&a
Health Lab
The First Vaccines for COVID-19: What We Know So Far
COVID-19 vaccines are here. Michigan Medicine experts share what we know about how these mRNA vaccines work, their ingredients, their efficacy and their safety.
 man talking with doctor in office
Health Lab
COVID-19 Vaccine Trial Volunteers Explain Why They Signed Up
COVID-19 vaccine trial volunteers explain why they signed up.
 drawing of pills on lined paper in blue ink
Health Lab
Big Costs for Small Patients with Rare Diseases, Study Finds
Percentage of all child health spending that went to orphan drugs rose 65% in five years, while families’ portion rose even faster.
 yellow sand clock on dark blue background
Health Lab
High Throughput Screening Identifies Molecules That Reduce Cellular Stress
While there is no actual fountain of youth, a new study shows a high throughput technique could help researchers find drugs that improve health and lengthen lifespan.
 drawing of a brain in blue ink on lined note paper
Health Lab
New Drug Combination May Slow Symptom Course Early on in ALS
Positive clinical trial points to possible additional option for patients with Lou Gehrig’s disease. A study investigator explains the excitement and the caution.
  • 1
  • 2
    •