Michigan Medicine researchers identify a potential therapeutic target for neurodegenerative conditions using animal models.

A tool borrowed from bacteria successfully seeks out, cuts and destroys long stretches of human cells’ DNA, opening doors to new uses in research and treatment.

An enzyme’s newly discovered ability to spur the body to prevent or repair acute liver injury could be harnessed as a therapy or used as a biomarker.

Groundbreaking new research marrying high-intensity focused ultrasound with genetically modified cells may spur bone and soft tissue regeneration.

A pilot study identifies a safe, effective strategy to help women with HIV have children in low-resource countries.

U-M researchers lead the field in successful protein creation, a tactic that could lead to a newer, more effective class of drugs.

Regulation of genes by noncoding DNA might help explain the complex interplay between our environment and genetic expression.

Examining the autoimmune disease at the molecular level led researchers to a specific molecule that could be contributing to the disease progression in patients.

The stable structure of circRNA makes it an ideal candidate for biomarkers. In addition, this type of RNA can be detected in blood or urine, making it potentially useful for cancer diagnosis or prognosis.

A laboratory-created microscopic network of fibers helped researchers understand how white blood cells capture and even kill bacteria, offering insight into the effectiveness of antibiotics in the future.

An enterprising science-based education program enlists clergy to help spread the word about HIV prevention and treatment.

A new and novel outcome measure is being used to determine effectiveness of new scleroderma treatments. Learn how Michigan Medicine is leading the way.  

Reactivating genes normally active before birth could prevent the harmful effects of a blood disorder with few treatment options.

With the help of a new human embryonic stem cell line, researchers make initial strides toward treatment for the genetic mutation.

A long-standing puzzle about long-term memory processing may be solved. The method: monitoring the brain activity of sleeping rats after they complete a new maze.