More articles about: Basic Science and Laboratory Research
ginger root in hands
Health Lab
Ginger Counters Certain Autoimmune Diseases in Mice
The main bioactive compound of ginger root lowers autoantibody production and helps halt disease progression in mice with antiphospholipid syndrome and lupus.
woman reacting to allergies outside with Kleenex behind bush with hat on
Health Lab
Uncovering Key Molecule that Drives Production of Cells Critical to Allergic Reactions
Researchers discover protein that regulates the gene expression for influential immune cells, paving a path for novel targets to treat inflammatory and allergic diseases.
grey transparent lungs seeing brachial branching
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Protein Linked to Progressive Lung Scarring in Scleroderma Patients
Osteopontin is discovered as the culprit behind these patients’ main cause of death. However, a repurposed immunosuppressive drug may combat the pro-inflammatory protein.
drawing of liver on lined paper in blue ink with a yellow badge with blue font on bottom right that says lab note
Health Lab
Amino Acid Connected to Fatty Liver Disease Could Provide Treatment Clues
Basic science research explores the effects of impaired glycine metabolism in nonalcoholic fatty liver disease and how to potentially use glycine-based treatment to help people with NAFLD.
green background with white mice on it
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The Link Between Obesity and Puberty
New research in mice shows that the hormone leptin may be a culprit in early puberty linked to childhood obesity.
white figured person standing next to a polygenetic risk score labeled A in green with a yellow dot and another person standing next to one labeled b with a red dot.
Health Lab
Democratizing Genetic Data for Cancer Research
An open access, online repository accelerates advancements in cancer prevention and prediction.
visual of four experts talking on a screen with the branding "lab note" on bottom right to indicate the section this story lives in on the blog
Health Lab
Researchers Argue for a More Systematic Use of Mathematical Models To Study Neurotechnologies
Study calls into question rush to use brain stimulation technology to treat Parkinson's and pain disorders.
Close up of ecoli bacteria
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Bad Bacteria Make Their Own Food to Colonize the Gut
How E coli. and other illness-causing bugs get past the microbiome’s defenses.
Health Lab
COVID-19 Through the Lens of Basic Science
Watch four Michigan Medicine experts discuss the role of fundamental science in ending the COVID-19 pandemic.
drawing on lined paper of heart in blue ink
Health Lab
Weakened Hearts Linked to a Build-Up of Phosphate
A computer simulation reveals the metabolic dysfunction behind heart failure.
yellow sand clock on dark blue background
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High Throughput Screening Identifies Molecules That Reduce Cellular Stress
While there is no actual fountain of youth, a new study shows a high throughput technique could help researchers find drugs that improve health and lengthen lifespan.
blood pressure dial with green yellow and red with mouse
Health Lab
High Blood Pressure Linked to Baroreflex in Rats
Animal model observation may reveal new cause of hypertension.
doctor and patient talking in a room
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Bringing Precision Medicine to Ophthalmology
Innovative device ensures doctors obtain adequate fluid samples from the eye, helping with diagnosis and individualized treatment plans for patients.
HIV attacking cells in purple pink and red
Health Lab
Antibiotic Molecule Enables Immune System to Kill HIV Infected Cells
New research shows that targeting a protein called Nef with a molecule called concanamycin A allowed the immune system to essentially cure HIV in T cells.
microscope drawn in blue ink on notepad paper
Health Lab
Immune Cell CXCR3 Receptor Behind Lethal Brain Damage Following Treatment for Fungal Infection
Finding could improve outcomes for treatment of infections in people living with HIV.